The Ipamorelin + CJC-1295 (No DAC) stack is the most popular GH secretagogue combination in the community. This article aggregates community experience reports for this combination.
Why This Stack Is So Popular
Ipamorelin stimulates GH release through the ghrelin receptor, while CJC-1295 (No DAC) is a GHRH analogue that amplifies the GH pulse. Together, they produce a synergistic GH pulse that is significantly larger than either compound alone. The community consistently reports this as the most effective GH secretagogue stack for body composition and sleep quality.
What the Community Reports
The most consistently reported early effect is dramatically improved sleep quality — particularly deep sleep and vivid dreams. This is typically reported within the first 1–2 weeks. Body composition changes (increased lean mass, reduced body fat) are reported over longer cycles of 12–16 weeks. Recovery from training is also frequently mentioned as improved.
Community Protocol
The most common community protocol is 200–300mcg of each compound administered subcutaneously before bed, 5 days on / 2 days off. Cycling off for 4 weeks after 12–16 weeks on is the standard approach to prevent receptor desensitization.